Rachael Leigh Cook smashes more than eggs in her latest This Is Your Brain on Drugs public service announcement. Optimus Prime, leader of the Autobots, falls prey to prostate cancer. The outcome is never in doubt during "World's Most One-Sided Fistfights Caught on Film." Outtakes from The Dukes of Hazzard, The X-Files, Battlestar Galactica and more come to light in "Bloopers." Rated TV-14-D.Skits: "Bush Message", "Santa Crash", "Public Service Announcement", "Teletubby smoking", "Cancer Pt. 1", "One Sided Fistfights", "Wizard of Oz", "Cancer Part 2", "X-span Request Live", "I'm so hungry", "Bloopers!"
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