In the year 2009, Yuji Kaido is an average young adult male diagnosed with a serious disease (the "B-cells") and is put into cryogenic stasis until a cure is found. Twenty-two years later, he is awakened in the midst of a raging war between armored soldiers and insectoid beings called the "Blue" which have overrun the Earth.
The soldiers are from an orbiting space colony collectively called Second Earth and were ordered to recover "sleepers" around the Earth. Among them is Marlene Angel, who at first appears to be heartless toward others. On the journey to Second Earth, Yuji meets many of the humans that were left behind during the evacuation due to limited resources. Standing orders for Marlene and the other troops are to consider any human survivors on the surface to be already dead, which greatly troubles Yuji.
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