Issue 121 (June 1973 by Conway-Kane-Romita) featured the death of Gwen Stacy at the hands of the Green Goblin in "The Night Gwen Stacy Died." Her demise and the Goblin's apparent death one issue later formed a story arc widely considered as the most defining in the history of Spider-Man. The aftermath of the story deepened both the characterization of Mary Jane Watson and her relationship with Parker.
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